Tuesday, June 07, 2005

How Many Stem Cell Lines Was That, Again? (continued)

With reference to the post above, have a look at the table below, and the sources I have listed below it.

 
Total # lines ever claimed "existing"
#  lines acctd for
# lines avail
# lines not avail
Explanation
 
 
 
 
not avail for shipping
will never be available
did not exist 8/9/01
 
BresaGen, Inc., Athens, GA
4
4
3
 -
1
1
failed to expand into undifferentiated cell cultures (i.e., did not become a stem cell line)*
Cell & Gene Therapy Research Institute, Korea
2
2
-
2
 -
none
Cellartis AB, Sweden
3
3
2
 -
1
withdrawn by donor**
CyThera, Inc., San Diego, CA
9
9
-
 -
9
9
failed to expand into undifferentiated cell cultures (i.e., did not become a stem cell line)*
ES Cell International, Singapore
6
6
6
 -
 
 
 
Geron Corp, Menlo Park, CA
7
7
-
 -
7
7
Geron Corp. of Menlo Park, Calif., does not, and did not at the time of the pronouncement, have seven cell lines. The cell lines attributed to Geron are the same lines attributed to WiCell and UCSF, and a full 8 days before Bush's announcement, testimony was given before the Senate Appropriation's committee that made this very clear. It was also confimed two years later by Geron in its response to NIH's' query about its cell lines.***
Goeteborg Univ, Sweden
16
1
-
1
?
?
none - 15 "lines" no explanation
Karolinska University, Sweden
6
6
-
 -
6
6
failed to expand into undifferentiated cell cultures (i.e., did not become a stem cell line)*
Maria Biotech Co., Korea
3
3
-
 -
3
 -
only available to Korean scientists****
MizMedi Hospital, Seoul N. Korea
1
1
1
 -
 
 -
 
National Centre for Biological Sciences, India
3
3
-
 -
3
3
as of May 2002, India had prohibited the export of human cells until it developed a national policy for doing that sort of business, but in the case of these three "lines," as of 2003, NCBS had not yet even attempted to expand these cells, therefore they could not have been "lines" in 2001.*****
Reliance Life Sciences, India
7
7
-
 -
7
 -
as of May 2002, India had prohibited the export of human cells until it developed a national policy for doing that sort of business******
Techion Israel lnstitute of Technology
4
8
3
5
 -
 -
none
UCSF
2
2
2
 -
 -
 -
 
WiCell Research Institute, WI
5
5
5
 -
 -
 -
 
TOTALS
78
67
22
8
37
26
 


Sources as of 6/5/04

*NIH classification which means that these stem cells failed to become "lines," and a line is defined as "a permanently established cell culture that will proliferate indefinitely given appropriate fresh medium and space." Obviously, if they have failed to become lines since 8/9/01, they were not lines at that time. . http://stemcells.nih.gov/research/registry/ and http://stemcells.nih.gov/research/registry/unavailable/

**http://stemcells.nih.gov/research/registry/cellartis.asp

***http://stemcells.nih.gov/research/registry/unavailable/geron.asp, http://appropriations.senate.gov/releases/record.cfm?id=177851

****http://stemcells.nih.gov/research/registry/unavailable/maria.asp

*****http://stemcells.nih.gov/research/registry/unavailable/ncbs.asp, http://www.genomenewsnetwork.org/articles/10_03/stem_cell_us_lines.php, http://www.washingtonpost.com/ac2/wp-dyn?pagename=article&contentId=A24621-2004Mar2¬Found=true, http://www.mult-sclerosis.org/news/May2002/StemCellResearchRunsIntoRoadblocks.htm

******http://stemcells.nih.gov/research/registry/unavailable/, http://www.genomenewsnetwork.org/articles/10_03/stem_cell_us_lines.php, http://www.washingtonpost.com/ac2/wp-dyn?pagename=article&contentId=A24621-2004Mar2¬Found=true, http://www.mult-sclerosis.org/news/May2002/StemCellResearchRunsIntoRoadblocks.html

Total # of lines ever counted as existing:
http://stemcells.nih.gov/research/registry/eligibilityCriteria.asp

# of lines listed as either available or not available (# of lines accounted for):
http://stemcells.nih.gov/research/registry/index.asp
http://stemcells.nih.gov/research/registry/unavailable/

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